SOD (Superoxide dismutase)
Reference : KB03011
Specifically, one unit of SOD corresponds to the amount of enzyme needed to exhibit 50% dismutation of the superoxide radical.
Superoxide dismutases (SODs) are metallo enzymes that catalyse the dismutation of the superoxide anion to molecular oxygen and hydrogen peroxide. Thus, it forms a crucial part of the cellular antioxidant defense mechanism. This SOD Activity Assay Kit uses a tetrazolium salt for detection of superoxide radicals. Particularly, xantine oxidase and hypoxantine are the enzymes that generate these radicals.
Excessive reactive oxygen species, especially superoxide anion (O2•−), play important roles in the pathogenesis of many cardiovascular diseases, including hypertension and atherosclerosis. Superoxide dismutases (SODs) are the major antioxidant defense systems against O2•−. There are three isoforms of SOD in mammals: the cytoplasmic Cu/ ZnSOD (SOD1), the mitochondrial MnSOD (SOD2), and the extracellular Cu/ZnSOD (SOD3). These enzymes require catalytic metal (Cu or Mn) for their activation.
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Specifications
Reference | Packaging | |
---|---|---|
KB03011-100 | 100 tests (96 puits/wells format) | |
KB03011-200 | 200 tests (96 puits/wells format) | |
KB03011-400 | 400 tests (96 puits/wells format) |